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1: |
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Nucleophosmin/anaplastic
lymphoma kinase (NPM/ALK) oncoprotein
induces the T regulatory cell phenotype by activating STAT3. |
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2: |
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Mantle cell lymphoma cells express predominantly Cyclin D1a isoform and are
highly sensitive to selective inhibition of CDK4 kinase
activity. |
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3: |
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Expression and oncogenic role of
Brk (PTK6/Sik) protein tyrosine kinase
in lymphocytes. |
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4: |
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Multi-gene epigenetic silencing of tumor suppressor genes
in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal
of the silencing. |
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5: |
Marzec M, Kasprzycka M, Ptasznik A,
Wlodarski P, Zhang Q, Odum N, Wasik MA. |
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Inhibition of ALK enzymatic activity in T-cell lymphoma
cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3. |
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6: |
Wlodarski P, Kasprzycka M, Liu X, Marzec
M, Robertson ES, Slupianek A, Wasik MA. |
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Activation of mammalian target of rapamycin
in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase
kinase, insulin growth factor-I, and serum. |
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7: |
Zhang
Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA. |
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STAT3- and DNA methyltransferase
1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase
tumor suppressor gene in malignant T lymphocytes. |
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8. Michal Marzec, Monika Kasprzycka, Xiaobin Liu, Raghunath PN, Pawel Wlodarski, Mariusz A. Wasik. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf. Oncogene, in press
9, S-H Jo, C Yang, Q Miao, M Marzec, MA Wasik, P Lu, YL Wang. PPARg promotes lymphocyte survival through its actions on cellular metabolic activities. J Immunol, 2006 in press.
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